As the US is fighting hard to flatten the curve and get ahead of the coronavirus pandemic, healthcare efforts are undoubtedly the need of the hour, but the path to the end-state can be accelerated by executing additional data driven tactics simultaneously. Social distancing is critical to check the spread of COVID-19, but relying on one strategy for the entire population won’t work and is not sustainable for the economy in the long run. A layered approach based on health risk stratification, the Susceptible, Exposed, Infected, or Recovered/Immune (SEIR) classification, and critical care needs can help put in place targeted actionable strategies and policies to save citizens’ lives and get America back on its feet.